NPPB and pulmonary arterial hypertension: Lower baseline and posttreatment levels of BNP are associated with improved survival.38 Other potential biomarkers that may be useful tools for predicting prognosis, monitoring disease progression, and assessing response to treatment include troponins, uric acid, d-dimer, and renal function.38 Although it is unlikely that one biomarker will replace the need for the current diagnostics, with more research the use of multiple biomarkers could play a larger role in the initial assessment and guide management of PAH.32