IL22 and colitis: Indeed, altered glycosylation during colitis and its impact on the microbiota is supported by recent evidence that IL22-induced Fut2 expression on epithelial cells of the small intestine increases the expression of fucose-degrading enzymes in the microbiota—changes which contribute to host recovery (Pickard et al., 2014) and protection against invading pathogens (Pham et al., 2014; Pickard et al., 2014).