TUSC7 and metastatic malignant neoplasm in the lymph nodes: In human pancreatic ductal adenocarcinoma (PDAC) and CRC, by analyzing the association of TUSC7 expression with clinicopathologic features, it was found that low TUSC7 expression was closely correlated with lymph node metastasis, liver metastasis, and more distant metastases [19, 22].