We further analysed the haplotypes of 6 tag SNPs out of 14 MPP7 SNPs (see Additional file 7) and the haplotype with ‘A’ allele at the fifth position (GAAGAC) for rs10763643, was found to be associated as a risk haplotype for POAG (p = 6.97X10−5). Here, MPP7 is linked to open-angle glaucoma.