In contrast, apoM (OR = 1.095, 95 % CI = 1.034–1.160, P = 0.002), smoking history (OR = 2.542, 95 % CI = 1.188–5.440, P = 0.016), and hs-CRP (OR = 1.249, 95 % CI = 1.136–1.374, P < 0.001) were found to be risk factors for COPD onset in the final model (Table 2). This evidence concerns the gene APOM and chronic obstructive pulmonary disease.