CXCL8 and hemolytic-uremic syndrome: Using a non-human primate model of HUS, after intravenous injections with Stxs, the baboons developed progressive thrombocytopenia, HUS with signs of glomerular thrombotic microangiopathy and systemic inflammatory responses in the baboon kidney, small intestine, colon, lung and spleen, with striking chemotactic profiling of highly expressed mRNAs for IL-8, MCP-1 and MIP-1α [163,164].