Furthermore, the upregulation of BMP4 in the tumour, which is a signaling cytokine growth factor, acting within the here enriched pathways of cancer, is also a noteworthy finding since BMP4 has been reported to be the top DE gene between clusters of AT/RT tumours with different survival outcome, showing a clear overexpression in tumours with short survival [19]. This evidence concerns the gene BMP4 and cancer.