The allele frequency of the SMARCB1 mutation in mRNA seq data was 75%, also supporting the loss of the wild type allele and the consequently biallelic inactivation of SMARCB1 in the tumour (but as in exome data not reaching a frequency of 100% due to some nontumor cells contamination, Supplementary Table 2). The gene discussed is SMARCB1; the disease is neoplasm.