TP53 and neuroblastoma: To determine the effects of RG7388 on neuroblastoma cells, we treated five neuroblastoma cell lines with RG7388: three cell lines had wild-type p53 (NGP, SH-SY5Y, and LAN-5) and two cell lines with silenced or null-mutated p53 (LAN-5 si-p53 and SK-N-AS).