Primary congenital glaucoma is a complex disease which has been mapped to at least three genetic loci viz GLC3A (GLC abbreviates to glaucoma, three means the congenital form of glaucoma and the suffix A, B and C reveals the chronological order of the deciphering of these loci) chromosome 2 (2p21);11 GLC3B―chromosome 1 (1p36);12 and GLC3C―chromosome 14 (14q24.3).13 The majority of PCG cases present with GLC3A involvement, specifically pointing toward CYP1B1 gene-based etiology. This evidence concerns the gene CYP1B1 and glaucoma.