The two ALS patients had a heterozygous C-to-G transition at nucleotide 1,550 (c.1550C>G) in the exon 15 coding sequence of the FUS gene (hereafter referred to as patient-1, FALS-e46, FALS-e48, and FALS-e54; and patient-2, FALS-2e2, FALS-2e3, and FALS-2e23). Here, FUS is linked to amyotrophic lateral sclerosis.