2001; Abe et al. 2010). Indeed, whereas the pulmonary vasculature in CH models begins to de‐remodel upon return to normoxic conditions, remodeling in the SuHx model continues to progress even after cessation of hypoxic exposure. However, whether PASMCs isolated from this model exhibit alterations in pHi homeostasis, NHE activity, or proliferation and migration remains unknown. The gene discussed is SLC9C1; the disease is cyclic hematopoiesis.