However, high levels of Gal-3 expression were also detected in BECs of patients with viral hepatitis B and C. Furthermore, intracytoplasmic and intranuclear overexpression of Gal-3 in BECs of patients with viral hepatitis B and C was also accompanied by intra-hepatocyte and extracellular overexpression of Gal-3 around inflammatory infiltrates. The gene discussed is LGALS3; the disease is hepatitis B virus infection.