FERMT1 and Kindler syndrome: Loss of Kindlin 1 (Kin1) in humans leads to the skin disorder known as Kindler Syndrome (KS) (Siegel et al., 2003), which is characterized by skin blistering, atrophy, photo-sensitivity, and a predisposition to aggressive squamous cell carcinomas (Siegel et al., 2003; Emanuel et al., 2006; Lai-Cheong et al., 2009).