CD28 and neoplasm: Mice that were treated either with Gvax or with Gvax plus P60 displayed a slight inhibition in tumor growth, while those mice that were treated with the whole combination (Gvax, P60 and MRP1-CD28 bi-specific aptamer) had a significant inhibition in tumor growth (Figure 5B) and around 50% survival rate in 50 days of follow-up (Figure 5C).