In consistent, knockdown of RIG-I reverses the effect of lncRNA Ftx siRNA, while ectopic expression of RIG-I counteracts the effect of lncRNA Ftx in Hep3B and SMMC-7721 HCC cell viability, colony formation, proliferation and cell cycle progression (respectively, P<0.05, Figure 7F-7J). This evidence concerns the gene RIGI and hepatocellular carcinoma.