IL10 and common variable immunodeficiency: Given the fact that CD24hiCD38hi and CD24hiCD27hi B cells were reduced in CVID patients we assessed IL-10 production in these subsets and found that CVID patients have decreased frequencies of IL-10-producing CD24hiCD38hi B cells in the different cell culture conditions and decreased frequency of IL-10-producing CD24hiCD27+ B cells stimulated with CpG+PIB.