MLR analysis, using a Wald chi-square p-value of <0.1 in the backward selection process, retained all six factors that were identified by ULR as positive predictors of SVR: younger age (p<0.0001), lower bodyweight (p = 0.0012), absence of cirrhosis (p = 0.0001), lower ALT ratio (p = 0.0203), higher platelet count (p = 0.0680) and lower HCV RNA level (p = 0.0015) (Fig 9 and S3 Table). The gene discussed is GPT; the disease is Cirrhosis.