Although the underlying molecular mechanisms for upregulation of miR‐1207‐5p in the colonic mucosa of AAs is unknown, our observation of an increased PVT1, a lncRNA, and p53‐inducible target gene downstream of well‐known cancer risk locus MYC, 48, 49, 50, 51 suggests a role of this lncRNA in regulating this process. The gene discussed is PVT1; the disease is cancer.