RAD51 and Friedreich ataxia: Interestingly, however, it has been shown that biallelic, null germline mutations in BRCA2 [10–14] and PALB2 [15–17], hypomorphic mutations in BRCA1 [18,19] and Rad51C [20], or in the case of RAD51 [21] a dominant mutation, all give rise to a spectrum of clinical symptoms that have features of Fanconi Anaemia (FA).