MERTK and myeloid sarcoma: We found that, consistent with the discordant association in the presence or absence of DR15, the allele associated with high expression of MERTK was associated with a decreased prevalence of MS in DR15 positive homozygotes, and a higher prevalence of MS in the absence of DR15. These data highlight the potential of MERTK as a therapeutic target, although the DR15 status of the patient would likely determine whether activation or repression of MERTK signalling would be the appropriate intervention.