Notch mediated changes to β‐dystroglycan in concert with the depletion of α‐dystroglycan laminin binding by hypo‐glycosylation [Bao et al., 2009; de Bernabe et al., 2009; Shimojo et al., 2011; Esser et al., 2013] is likely to contribute significantly to the tomourigenic potential of prostate cancer. Here, LAMB2 is linked to prostate cancer.