MEN1 and adrenal gland neoplasm: We therefore assessed the antiproliferative effects of the multireceptor-targeted SA pasireotide (24) in pancreatic and pituitary NETs that develop in an established mouse model for MEN1 (29), in which mice deleted for an allele of the Men1 gene (ie, heterozygous (Men1+/−) mice) develop pancreatic and pituitary NETs in association with parathyroid and adrenal tumors.