HSPA1A and essential hypertension: Fig 2A represents the individual delta-CT value of study subjects. The average delta-CT value for patients and controls were found to be 4.03 ± 0.07 and 6.72 ± 0.09, respectively, and the difference in the delta-CT values were found to be statistically significant (P < 0.001) (Fig 3). The relative expression of mRNA for HSP70 gene to 18S rRNA in patients with essential hypertension was increased by approximately 6.45 fold as compared to control.