Small soluble amyloid oligomers deriving from a variety of proteins in very different tissues have recently been suspected to lead to pathologies in many amyloid diseases, such as AD (Aβ), Parkinson's (α-synuclein), Huntington's (huntingtin), type-2 diabetes (islet amyloid polypeptide, IAPP), and prion diseases [2]. Here, IAPP is linked to Parkinson disease.