Accordingly, recent work indicates that skin papillomas induced by DMBA+TPA in mice can be strongly reduced in size and frequency by homozygous deletion of YAP along with one copy of TAZ or by treatment with Dasatinib (Creedon and Brunton, 2012; Serrels et al., 2009; Zanconato et al., 2015). Here, YAP1 is linked to skin papilloma.