2) In contrast, as reported in HCC (hepatocellular cancer) [34], H19 expression was down-regulated and associated with the protein complex hnRNP U/PCAF/RNAPol II, which activates the miR-200 family by increasing the histone acetylation, thus contributing to the suppression of tumor metastasis. Here, KAT2B is linked to hepatocellular carcinoma.