PRRT2 and neoplasm: A large body of evidence supports this, for example, overexpression of PKCε is a suggested tumour promoter in stomach, lung, thyroid, colon and breast cancer [4], increased levels of PKCη are associated with tumour aggressiveness and an increased rate of cell proliferation in non-small-cell lung cancer [21] and overexpression of PKC θ is linked to gastrointestinal stromal tumours [22].