MAPK15 and neoplasm: Therefore, to evaluate the role of autophagy controlled by MAPK15 in in vivo tumor formation by NTera2/D1, we injected these cells stably expressing empty vector and WT, AXXA and KD MAPK15 mutants, in athymic nude-Foxn1nu/nu mice and monitored their tumor growth over a time span of approximately 4 weeks.