Anti-TNF agents prescribed by non-rheumatologists were used for both inflammatory and non-inflammatory disorders diagnosed after the initial back pain diagnosis date, including RA (26.9 %), back disorder not specified (18.2 %), spondylosis (18.2 %), rheumatism not otherwise specified (15.2 %), joint effusion (15.2 %), and osteoarthritis (9.1 %). This evidence concerns the gene TNF and spondylosis.