NORE1A has been reported to act as a tumour suppressor that upon expression can lead to a decrease in the number of cells in S phase of the cell cycle via a G1 growth arrest.15 Therefore, we examined whether mCD40L-induced NORE1A expression contributes to the mCD40L-induced cell death in CD40-positive carcinomas. The gene discussed is RASSF5; the disease is carcinoma.