In an attempt to select egg-derived bioactive peptides with potential to treat cardiometabolic disorders, such as obesity, dyslipidemia, diabetes and hypertension, we carried out an in vitro screening of egg white hydrolysates produced with food-grade enzymes from different sources, on the basis of their antioxidant, anti-inflammatory, bile acid binding (hypocholesterolemic related marker), dipeptidyl peptidase IV (DPP IV) (glucose metabolism related marker) and angiotensin converting enzyme (ACE)-inhibitory activities [13]. This evidence concerns the gene DPP4 and diabetes mellitus.