Given the crucial role of STARD13-, CDH5-, HOXD1-, and HOXD10-3’UTRs in breast cancer metastasis, we believe that STARD13-, CDH5-, HOXD1-, and HOXD10-3’UTRs could be therapeutic targets for the development of anti-metastatic strategy for breast cancer treatment in the near future. This evidence concerns the gene HOXD1 and breast cancer.