CXCL12 is associated infiltrating leukocytes, CXCR7 antagonist inhibited function of CXCL12, so CXCR7, a CXCL12 receptor), impacted both MS severity and recovery during EAE [21], however, CXCR6 is required for T cell infiltration into spinal cord following cortical injury [22]. The gene discussed is CXCL12; the disease is myeloid sarcoma.