Carcinoma cells in tissues with stromal beclin 1 positivity had higher Ki-67 LI than those without its positivity (p = 0.042 for hot spot Ki67 and 0.0075 for overall average Ki67, N = 53; Fig. 4a), suggesting the correlation between stromal beclin 1 expression and carcinoma cell proliferation. This evidence concerns the gene MKI67 and carcinoma.