IL6 and infection: To evaluate the infection in the staphylococcal osteomyelitis model, we measured the serum interleukin-6 (IL-6) and C-reactive protein (CRP) in retro-orbital blood samples collected before surgery and on post-surgical days 1, 3, 7, and 14 from mice in the control and ionic-silver groups (n = 3, 3).