Many studies have demonstrated that the downregulation of the members of the β-catenin destruction complex, including CK1α, is commonly observed in lung cancer cell lines and cancer tissue and correlates with poor prognosis or poor clinicopathological characteristics (Yang et al., 2013; Srivastava et al., 2012; Lee et al., 2013). This evidence concerns the gene CSNK1A1 and lung cancer.