MTDH and ovarian carcinoma: Two studies conducted on blood samples from breast and ovarian cancer patients have analyzed the coding sequence of MTDH, and identified a correlation between the polymorphisms c.1353G > A (rs2331652, p.K451K), and c.1679–6 T > C (rs117026063), and breast cancer susceptibility as well as between the polymorphism −470 G > A and ovarian cancer susceptibility20, 24.