The decreased sensitivity to PFC GABAAR blockade in Df(h15q13)/+ mice is also in agreement with histological findings in patients with schizophrenia showing reduced cortical expressions in a range of GABAergic markers, including non-pyramidal cells (1991), PV-immunoreactivity (Beasley and Reynolds 1997), GAD65/67 levels (Akbarian et al. 1995), and GAT1 (Volk et al. 2001). Here, SLC6A1 is linked to schizophrenia.