It is now a well-understood phenomenon that animal models of heart diseases, such as ischemia [39–41], diabetic cardiomyopathy [5] and hypertensive/hypertrophic HF [14, 40, 42] result in increased Dio3, decreased MCT-10 (one of the important T3 transporters) along with fetal gene reexpression. This evidence concerns the gene SLC16A10 and ischemia.