ABCG1 and neoplasm: Whereas all engrafted mice harbored brain tumors, there was reduced tumor growth by BLI in the two K1861 Abcg1 shRNA groups (n = 10 mice/group) relative to control shRNA K1861-implanted mice (n = 10 mice) at 28 days post-injection (Figure 4A) and the bioluminescent signal was significantly reduced in both Abcg1 shRNA groups relative to control shRNA K1861-implanted mice (#1, p = 0.042; #2, p = 0.0098; Figure 4B).