In our study, we screened ten human bladder cell lines, ranging from immortalized urothelial cells (SV-HUC and TERT-NHUC) and low-grade bladder cancer cell lines to MIBC cell lines, finding high POSTN expression in MIBC lines J82, TCC-SUP, and UMUC3, consistent with a number of cell line survey reports [27–29]. The gene discussed is TERT; the disease is urinary bladder carcinoma.