Vδ1 T cells primarily exist in the intraepithelial layer of the skin and intestines, where they are involved in maintaining epithelial tissue integrity when suffering damage, infection, or transformation, responding to stress antigens on epithelial cells and secreting interleukin-10 (IL-10) but little or no interleukin-2 (IL-2), interleukin-4 (IL-4), or interferon-γ (IFN-γ) [12–15]. The gene discussed is IL2; the disease is infection.