The results of this study included an initial significant association of Alanine Aminotransferase with periodontitis (odds ratio 1.30, 95% CI, 1.02, 1.65), which remained positive but attenuated and failed to reach significance with the addition of other variables (adjusted odds ratio 1.17, 95% CI, 0.85, 1.60). This evidence concerns the gene GPT and periodontitis.