PROM1 and peripheral arterial disease: In this study, after successful endovascular infra-aorta revascularization of the macroblood vessels, we enriched CD133+ cells from peripheral blood derived mononuclear cells (MNCs) and reinfuse the cells intra-arterially through a catheter to improve the microvascular angiogenesis, evaluating their efficacy and immune-regulatory impact on diabetic subjects with PAD.