NES and embryonal carcinoma: Similarly, in common tumor cell line models of human neural differentiation, YAP was more prominently expressed in the less mature, embryonal carcinoma-derived NTERA2 cell line (nestin-postive, doublecortin-negative, TUJ1-negative) when compared to the SH-SY5Y neuroblastoma cell line, which contains nestin-positive as well as TUJ1- and doublecortin-positive subsets (Fig. 1d; Supplementary Fig. 1c–e).