EGFR and neoplasm: In regards to cytologic tumor markers, only c-CYFRA was significantly different between EGFR status, with higher levels of c-CYFRA with EGFR mutations compared with wild-type EGFR (200.2 ng/ml ± 208.8 ng/ml vs 85.2 ng/ml ±135.8 ng/ml, p = 0.014).