FCGR2A and neoplasm: Using the same approaches as described above, we found that even at a low ratio of CMPs vs splenocytes (1:8), CMPs (Lin−IL-7R−Sca-1−c-kit+CD34+FcRII/IIIlo/− cells26, 27, 28) from either tumor-bearing mice (T-CMP) or normal mice (N-CMP) caused a dramatic reduction in T-cell proliferation stimulated by polyclonal stimuli (Fig. 2C) or allo-antigens (Fig. 2D).