Both the solid-ordered CAF01 and CAF04 and the liquid-crystalline, cationic DOTAP:DOPC-liposomes loaded with poly(I:C) via electrostatic surface attachment induce strong CD8+ T-cell responses against several different antigens (OVA, E7, the cancer antigen TRP-2, the TB vaccine antigens TB10.3-P1 and H56 and the HIV vaccine antigen Gag p24) in mice [83,84,85,87]. Here, CD8A is linked to cancer.