Lnc-2 and lnc-6 showed a consistently positive correlation in expression with PTEN in the memorial sloan kettering cancer center (MSKCC)24 (rlnc-2-PTEN=0.32, plnc-2-PTEN<5.89x10−5, rlnc-6-PTEN=0.45, plnc-6-PTEN<5.89x10−9) cohort and Mayo Clinic29 (rlnc-2-PTEN=0.48, plnc-2-PTEN<1.62x10−32, rlnc-6-PTEN=0.47, plnc-6-PTEN<1.66x10−31) cohort (Fig. 3a). This evidence concerns the gene PTEN and cancer.