It’s down-regulated and the target genes DCBLD2, FOXN3, IKZF1, NPTN PAFAH1B1, USP10, YY1, ARHGAP1, ARHGEF3, BCL11B, C16orf5, CNTNAP1, FOXN3, FUT8, IL6R, ITGB8, ITSN1, JAG1, MLL2, NDST1,NOTCH2, NPNT, PPFIA1, PTPRM, PVRL1, SERPINE1, VCL were up-regulated in NPC [18]. This evidence concerns the gene PTPRM and nasopharyngeal carcinoma.