The target genes of miR-29c such as BCL2L2, HBEGF, HBP1, HSPG2, ITGB1, LAMC2, LTBR, MIB1, MLF1, MMP2,NDST1,SVEP1MCL-1,BCL-2,TIAM1 were up-regulated and miR-29c could sensitize NPC cells to ionizing radiation and cisplatin treatment by promoting apoptosis [10, 11, 18]. The gene discussed is HSPG2; the disease is nasopharyngeal carcinoma.