It’s down-regulated and the target genes DCBLD2, FOXN3, IKZF1, NPTN PAFAH1B1, USP10, YY1, ARHGAP1, ARHGEF3, BCL11B, C16orf5, CNTNAP1, FOXN3, FUT8, IL6R, ITGB8, ITSN1, JAG1, MLL2, NDST1,NOTCH2, NPNT, PPFIA1, PTPRM, PVRL1, SERPINE1, VCL were up-regulated in NPC [18]. Here, YY1 is linked to nasopharyngeal carcinoma.